李楠,女,1989年生于陕西西安,理学博士,副教授,硕士生导师。2011年毕业于西北大学,获理学学士学位;2016年毕业于中国科学院化学研究所,获理学博士学位。历任中国农业科学院农业质量标准与检测技术研究所助理研究员、副研究员。现任教于新材料与化工学院制药工程系。长期致力于复杂样品中药物及其代谢物检测新材料与新技术研发。先后主持承担国家自然科学基金面上项目、青年项目,国家重点研发计划项目子课题等10余项,荣获神农中华农业科技奖、全国农牧渔业丰收奖、中国农业科学院科学技术成果奖、中国分析测试协会科学技术奖等一等奖4项,以第一/通讯作者身份在Journal of Hazardous Materials, Analytical Chemistry, ACS applied materials & interfaces, Talanta, Journal of chromatography A等期刊发表SCI论文13篇,累计影响因子50以上,申请国家发明专利11项,其中6项已授权。
I. 主要研究工作
1. 生物医药快速检测技术研发;
2. 生物医药分离富集材料研发;
3. 未知有机有害物质化学结构鉴定及标准物质合成。
II. 学术奖励
1. 全国农牧渔业丰收奖“畜禽产品重点危害因子快速精准检测关键技术及应用”,一等奖,2019-2021.
2. 神农中华农业科技奖“农产品中主要危害因子高效识别与风险评估关键技术及应用”,一等奖,2020-2021.
3. 中国农业科学院科学技术成果奖“主要农产品风险因子识别与安全评价关键技术研发及应用”,一等奖,2020.
4. 中国分析测试协会科学技术奖“构建聚合物分子温度剂及其细胞成像应用研究”,一等奖,2016.
III. 主持承担项目
1. 国家自然科学基金面上项目:富硫蔬菜中氯代苯类农药新型含硫代谢物形成机制及风险评估(项目号:32372445),项目负责人,2024-2027.
2. 国家自然科学青年基金项目:识别氨基糖苷类抗生素的比率型荧光印迹阵列传感基础研究(项目号:21804138),项目负责人,2019-2021.
3. 国家重点研发计划项目子课题:畜禽类地理标志产品特色风味品质挖掘及指纹构建(项目号:2022YFF0606801),项目负责人,2022-2026.
4. 农业农村部财政项目:果蔬产品中新型代谢物巯基百菌清残留风险评估(项目号:2022110043007955),项目负责人,2022.
IV. 代表性学术论文
1. Yilin Cao, Nan Li*, Yun Li, Jing Qiu, Haixia Sui, Daoyuan Yang, Yongzhong Qian*. Sulfhydrylation of chlorothalonil in the pak choi from the cultivation to sample analysis and the exposure risk assessment. Journal of Hazardous Materials, 2025, 485, 136920.
2. Nan Li, Yining Xia, Yun Li, Qi Jia, Jing Qiu*, Yanyang Xu, Zian Wang, Zhe Liu, Yongzhong Qian*. Untargeted screening, quantitative analysis, and toxicity estimation of degradation products of fluazinam in vegetables. Microchemical Journal, 2023, 190, 108584.
3. Nan Li, Yining Xia, Yanyang Xu, Yun Li, Qi Jia, Jing Qiu*, Yongzhong Qian*, Zian Wang. Identification and analysis of the degradation products of chlorothalonil in vegetables. Journal of Chromatography A, 2022, 1686, 463647.
4. Nan Li, Jing Qiu*, Yongzhong Qian. Polyethyleneimine-modified magnetic carbon nanotubes as solid-phase extraction adsorbent for the analysis of multi-class mycotoxins in milk via liquid chromatography-tandem mass spectrometry. Journal of Separation Science, 2021, 44, 636-644.
5. Nan Li, Jing Qiu*, Yongzhong Qian. Amphiphilic block copolymer-grafted magnetic multi-walled carbon nanotubes as QuEChERS adsorbent for simultaneous determination of mycotoxins and pesticides in grains via liquid chromatography tandem mass spectrometry. Microchimica Acta, 2020, 187, 648.
6. Huiying Liu, Nan Li*, Xubo Liu, Yongzhong Qian, Jing Qiu, Xiaoning Wang. Poly(N-acryloyl-glucosamine-co-methylenebisacrylamide)-based hydrophilic magnetic nanoparticles for the extraction of aminoglycosides in meat samples. Journal of Chromatography A, 2020, 1609, 460517.
7. Nan Li, Jing Qiu*, Huiying Liu, Zhijun Chen, Yongzhong Qian. Thermoregulated extraction of luteolin under neutral conditions using oligo(ethyleneglycol)-based magnetic nanoparticles with Wulff-type boronate affinity. Journal of Chromatography A, 2019, 1607, 460396.
8. Nan Li, Yue Song, Jing Qiu*, Yuechen Zhao, Yongzhong Qian. Polymer brushes-containing coordination polymer networks on monolith for rapid solid phase extraction of multi-class drug residues in meat samples. Talanta, 2018, 185, 573-580.
9. Nan Li, Li Qi*, Juan Qiao, Yi Chen. Ratiometric and selective protein detection based on dissociation of aqueous polymer-pyrene/g-cyclodextrin inclusion complex. Analytical Chemistry, 2016, 88: 1821-1826.
10. Nan Li, Ying Shen, Li Qi *; Zhibo Li, Juan Qiao, Yi Chen. Preparation of an amino acid-based polymer monolith for trimodal liquid chromatography. RSC Advances, 2015, 5, 61436.
11. Nan Li, Li Qi*, Ying Shen, Juan Qiao, Yi Chen. Novel oligo(ethylene glycol)-based molecularly imprinted magnetic nanoparticles for thermally modulated capture and release of lysozyme. ACS Applied Material &Interfaces, 2014, 6, 17289-17295.
12. Nan Li, Wei Zheng, Ying Shen, Li Qi*, Yaping Li, Juan Qiao, Fuying Wang, Yi Chen*. Preparation of a novel polymer monolith with functional polymer brushes by two-step atom transfer radical polymerization for trypsin immobilization. Journal of Separation Science, 2014, 37, 3411-3417.
13. Nan Li, Li Qi*, Ying Shen, Yaping Li, Yi Chen. Thermoresponsive oligo(ethylene glycol)-based polymer brushes on polymer monoliths for all-aqueous chromatography. ACS Applied Material &Interfaces, 2013, 5, 12441-12448.
14. Nan Li, Li Qi *, Ying Shen, Yaping Li, Yi Chen. Amphiphilic block copolymer modified magnetic nanoparticles for microwave-assisted extraction of polycyclic aromatic hydrocarbons in environmental water. Journal of Chromatography A, 2013, 1316, 1-7.
V. 发明专利
1.李楠,陈潮文,邱静,钱永忠,刘会影.一种聚苯乙烯-二乙烯基苯修饰的磁性纳米管复合材料及其应用.中华人民共和国发明专利,ZL202011425936.0,授权公告日:2020.12.08.
2.李楠,邱静,钱永忠.一种温敏 Wulff 型硼亲和纳米颗粒及其制备方法与用途. 中华人民共和国发明专利,ZL201910300674.6,授权公告日:2019.04.15.
3.李楠,李耘,邱静,钱永忠.一种聚乙烯亚胺功能化嵌段聚合物磁性纳米颗粒复合材料及其制备方法和应用.中华人民共和国发明专利,ZL201911383003.7,授权公告日:2019.12.27.
4.李楠,李耘,邱静,钱永忠.一种生物胺配位印迹材料、生物胺荧光阵列传感器及其制备方法和用途.中华人民共和国发明专利,ZL201911382993.2,授权公告日:2019.12.27.
5.李楠,邱静,钱永忠.基于聚单糖的温度响应型氨基糖苷类抗生素印迹磁性纳米颗粒及其制备方法和应用.中华人民共和国发明专利,ZL201811530175.8,授权公告日:2018.12.14.
6.李楠,邱静,钱永忠,宋月.聚合物整体柱、基于所述整体柱的固相萃取过滤器及其制备方法和用途.中华人民共和国发明专利,ZL201710117790.5,授权公告日:2017.03.01.
VI. 招生信息
本人主要招收生物与医药类(0860)专业学位硕士(制药工程领域086002)。诚挚欢迎化学、高分子材料、分析化学等相关专业热爱科研、刻苦认真的同学加入本团队。